In the collaboration with Institute of Chemical Technology and Analytics (TU Wien) we ran the project on collecting both elemental and molecular information from the very same slice! The methods employed – µXRF for elemental and MALDI for molecular information. The sample on which we tested the workflow could be easily bought on market – chicken feet (phalanx section was measured). Yummy!
The project is described in the paper “Multimodal imaging of undecalcified tissue sections by MALDI MS and μXRF” published by Analyst.
Our group travels a lot this summer! Now we’re at the legendary European Synchrotron Radiation Facility (shortly ESRF) in France – the brightest source, the highest resolution – some 50nm and truly unique location!
The Seminar Activation Analysis and Gamma Spectroscopy (SAAGAS 26), took place on 19-22 February in TU Wien, Vienna, Austria. Our group from Atominstitut contributed to the Seminar 2 oral presentations, as well as 5 posters – and three of the posters were devoted to biological samples:
- Total X-ray reflection spectrometry of black tea and herbal infusions
- μXRF spectrometer of Atominstitut in bio-imaging application
- Confocal μXRF spectrometer for low to high Z element analysis
We’re very delighted to share, that the talk of Mirjam Rauwolf – “Synchrotron radiation micro XRF analysis of zinc in osteosarcoma tissue” received an award!
In the middle of February we traveled once again to Diamond synchrotron. This time we performed highly-resolved (1 micron!) XRF imaging of bone-cartilage samples. Thanks to the supportive team of B16 beamline, we’re going to visit you again soon!
The team at work:
The XRF-Bone team wishes you a happy new year!
And if your new year’s resolution is to read more papers, check out the early view online version of our newest paper – “Increased zinc accumulation in mineralized osteosarcoma tissue measured by confocal synchrotron radiation micro X-ray fluorescence analysis” which will be published in X-Ray Spectrometry.
Our new paper compares a confocal and a color X-ray camera setup. It will be published in the January 2017 issue of the Journal of Synchrotron Radiation. You can already read it online if you follow this link.
Great news from Italy! First of all, the needed improvements were made on our micro-XRF laboratory setup and we are having second wonderful beamtime at X-Ray fluorescence beamline at Elettra Syncrotrone, Trieste, Italy.
What is more, the paper “(Invited) ALD to Prevent Metal Transfer from Implants” (doi: 10.1149/07506.0167ecst), which is the result of collaboration with University of Brescia (Dr. Laura Borgese, Dr. Fabjola Bilo, Dr. Annalisa Zacco, Prof. Elza Bontempi, Dr. Michela Pasquali, Dr. Stefania Federici and Prof. Laura E. Depero) and for which micro-XRF spectrometer at Atominstitut was used, has been published.
successful beamtime = happy team
X-Ray Microscopy Conference 2016
Thanks to everyone who visited our posters in Chicago!
If you did not have a chance to see our work yet, we will be at the X-ray Microscopy Conference in Oxford – 15th to 19th August 2016.
We will present three posters on Monday 15th from 17:00 to 19:00:
Zinc Distribution In Human Bone: SR-Micro X-Ray Fluorescence Imaging of Osteoporotic Samples (S1-P3-05)
Exploitation of μXRF Spectrometer for Bio-imaging (S1-P3-06)
High resolution imaging of metal localization in cancer cells at the B16 beamline at Diamond.